Tuesday, 29 May 2012

PrimaCare One


Generic Name: prenatal multivitamins (PRE nay tal VYE ta mins)

Brand Names: Advance Care Plus, Bright Beginnings, Cavan Folate, Cavan One, Cavan-Heme OB, Cenogen Ultra, CitraNatal Rx, Co Natal FA, Complete Natal DHA, Complete-RF, CompleteNate, Concept OB, Docosavit, Dualvit OB, Duet, Edge OB, Elite OB 400, Femecal OB, Folbecal, Folcaps Care One, Folivan-OB, Foltabs, Gesticare, Icar Prenatal, Icare Prenatal Rx, Inatal Advance, Infanate DHA, Kolnatal DHA, Lactocal-F, Marnatal-F, Maternity, Maxinate, Mission Prenatal, Multi-Nate 30, Multinatal Plus, Nata 29 Prenatal, Natachew, Natafort, Natelle, Neevo, Nestabs, Nexa Select with DHA, Novanatal, NovaStart, O-Cal Prenatal, OB Complete, OB Natal One, Ob-20, Obtrex DHA, OptiNate, Paire OB Plus DHA, PNV Select, PNV-Total, PR Natal 400, Pre-H-Cal, Precare, PreferaOB, Premesis Rx, PrenaCare, PrenaFirst, PrenaPlus, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal Elite, Prenatal Multivitamins, Prenatal Plus, Prenatal S, Prenatal-U, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenavite FC, PreNexa, PreQue 10, Previte Rx, PrimaCare, Pruet DHA, RE OB Plus DHA, Renate, RightStep, Rovin-NV, Se-Care, Se-Natal One, Se-Plete DHA, Se-Tan DHA, Select-OB, Seton ET, Strongstart, Stuart Prenatal with Beta Carotene, Tandem OB, Taron-BC, Tri Rx, TriAdvance, TriCare, Trimesis Rx, Trinate, Triveen-PRx RNF, UltimateCare Advance, Ultra-Natal, Vemavite PRX 2, VeNatal FA, Verotin-BY, Verotin-GR, Vinacal OR, Vinatal Forte, Vinate Advanced (New Formula), Vinate AZ, Vinate Care, Vinate Good Start, Vinate II (New Formula), Vinate III, Vinate One, Vitafol-OB, VitaNatal OB plus DHA, Vitaphil, Vitaphil Aide, Vitaphil Plus DHA, Vitaspire, Viva DHA, Vol-Nate, Vol-Plus, Vol-Tab Rx, Vynatal F.A., Zatean-CH, Zatean-PN


What are PrimaCare One (prenatal multivitamins)?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.


Prenatal vitamins are a combination of many different vitamins that are normally found in foods and other natural sources.


Prenatal vitamins are used to provide the additional vitamins needed during pregnancy. Minerals may also be contained in prenatal multivitamins.


Prenatal vitamins may also be used for purposes not listed in this medication guide.


What is the most important information I should know about prenatal vitamins?


There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.


Never take more than the recommended dose of a multivitamin. Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.


Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the multivitamin.

What should I discuss with my healthcare provider before taking prenatal vitamins?


Many vitamins can cause serious or life-threatening side effects if taken in large doses. Do not take more of this medication than directed on the label or prescribed by your doctor.

Before taking prenatal vitamins, tell your doctor about all of your medical conditions.


You may need to continue taking prenatal vitamins if you breast-feed your baby. Ask your doctor about taking this medication while breast-feeding.

How should I take prenatal vitamins?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Never take more than the recommended dose of prenatal vitamins.

Many multivitamin products also contain minerals such as calcium, iron, magnesium, potassium, and zinc. Minerals (especially taken in large doses) can cause side effects such as tooth staining, increased urination, stomach bleeding, uneven heart rate, confusion, and muscle weakness or limp feeling. Read the label of any multivitamin product you take to make sure you are aware of what it contains.


Take your prenatal vitamin with a full glass of water.

Swallow the regular tablet or capsule whole. Do not break, chew, crush, or open it.


The chewable tablet must be chewed or allowed to dissolve in your mouth before swallowing. You may also allow the chewable tablet to dissolve in drinking water, fruit juice, or infant formula (but not milk or other dairy products). Drink this mixture right away.


Use prenatal vitamins regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.


Store at room temperature away from moisture and heat. Keep prenatal vitamins in their original container. Storing vitamins in a glass container can ruin the medication.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of vitamins A, D, E, or K can cause serious or life-threatening side effects and can also harm your unborn baby. Certain minerals contained in a prenatal multivitamin may also cause serious overdose symptoms or harm to the baby if you take too much.

Overdose symptoms may include stomach pain, vomiting, diarrhea, constipation, loss of appetite, hair loss, peeling skin, tingly feeling in or around your mouth, changes in menstrual periods, weight loss, severe headache, muscle or joint pain, severe back pain, blood in your urine, pale skin, and easy bruising or bleeding.


What should I avoid while taking prenatal vitamins?


Avoid taking any other multivitamin product within 2 hours before or after you take your prenatal vitamins. Taking similar vitamin products together at the same time can result in a vitamin overdose or serious side effects.

Avoid the regular use of salt substitutes in your diet if your multivitamin contains potassium. If you are on a low-salt diet, ask your doctor before taking a vitamin or mineral supplement.


Do not take this medication with milk, other dairy products, calcium supplements, or antacids that contain calcium. Calcium may make it harder for your body to absorb certain ingredients of the prenatal vitamin.

Prenatal vitamins side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

When taken as directed, prenatal vitamins are not expected to cause serious side effects. Less serious side effects may include:



  • upset stomach;




  • headache; or




  • unusual or unpleasant taste in your mouth.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect prenatal vitamins?


Vitamin and mineral supplements can interact with certain medications, or affect how medications work in your body. Before taking a prenatal vitamin, tell your doctor if you also use:



  • diuretics (water pills);




  • heart or blood pressure medications;




  • tretinoin (Vesanoid);




  • isotretinoin (Accutane, Amnesteen, Clavaris, Sotret);




  • trimethoprim and sulfamethoxazole (Cotrim, Bactrim, Gantanol, Gantrisin, Septra, TMP/SMX); or




  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.



This list is not complete and other drugs may interact with prenatal vitamins. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More PrimaCare One resources


  • PrimaCare One Side Effects (in more detail)
  • PrimaCare One Use in Pregnancy & Breastfeeding
  • Drug Images
  • PrimaCare One Drug Interactions
  • PrimaCare One Support Group
  • 0 Reviews for PrimaCare One - Add your own review/rating


  • PrimaCare One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Cal-Nate MedFacts Consumer Leaflet (Wolters Kluwer)

  • CareNatal DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • CitraNatal 90 DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • CitraNatal Assure Prescribing Information (FDA)

  • CitraNatal Harmony Prescribing Information (FDA)

  • Concept DHA Prescribing Information (FDA)

  • Docosavit Prescribing Information (FDA)

  • Duet DHA with Ferrazone MedFacts Consumer Leaflet (Wolters Kluwer)

  • Folbecal MedFacts Consumer Leaflet (Wolters Kluwer)

  • Folcal DHA Prescribing Information (FDA)

  • Folcaps Care One Prescribing Information (FDA)

  • Gesticare DHA Prescribing Information (FDA)

  • Gesticare DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • Inatal Advance Prescribing Information (FDA)

  • Inatal Ultra Prescribing Information (FDA)

  • Multi-Nate DHA Prescribing Information (FDA)

  • Multi-Nate DHA Extra Prescribing Information (FDA)

  • MultiNatal Plus MedFacts Consumer Leaflet (Wolters Kluwer)

  • Natelle One Prescribing Information (FDA)

  • Neevo Caplets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Neevo DHA MedFacts Consumer Leaflet (Wolters Kluwer)

  • OB Complete 400 MedFacts Consumer Leaflet (Wolters Kluwer)

  • Paire OB Plus DHA Prescribing Information (FDA)

  • PreNexa Prescribing Information (FDA)

  • PreNexa MedFacts Consumer Leaflet (Wolters Kluwer)

  • PreferaOB Prescribing Information (FDA)

  • Prenatal Plus Prescribing Information (FDA)

  • Prenatal Plus Iron Prescribing Information (FDA)

  • Prenate Elite Prescribing Information (FDA)

  • Prenate Elite MedFacts Consumer Leaflet (Wolters Kluwer)

  • Prenate Elite tablets

  • Prenate Essential Prescribing Information (FDA)

  • PrimaCare Advantage MedFacts Consumer Leaflet (Wolters Kluwer)

  • PrimaCare ONE capsules

  • Renate DHA Prescribing Information (FDA)

  • Se-Natal 19 Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Se-Natal 19 Prescribing Information (FDA)

  • Tandem DHA Prescribing Information (FDA)

  • Tandem OB Prescribing Information (FDA)

  • TriAdvance Prescribing Information (FDA)

  • Triveen-One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Triveen-PRx RNF Prescribing Information (FDA)

  • UltimateCare ONE NF Prescribing Information (FDA)

  • Ultra NatalCare MedFacts Consumer Leaflet (Wolters Kluwer)

  • Vinate AZ Prescribing Information (FDA)

  • Vitafol-One MedFacts Consumer Leaflet (Wolters Kluwer)

  • Zatean-CH Prescribing Information (FDA)



Compare PrimaCare One with other medications


  • Vitamin/Mineral Supplementation during Pregnancy/Lactation


Where can I get more information?


  • Your pharmacist can provide more information about prenatal vitamins.

See also: PrimaCare One side effects (in more detail)


Monday, 28 May 2012

Fluoritab Drops


Pronunciation: SOE-dee-um FLOOR-ide
Generic Name: Sodium Fluoride
Brand Name: Examples include Fluor-A-Day, Fluoritab, and Kardium


Fluoritab Drops are used for:

Preventing cavities in children older than 6 months of age when the amount of fluoride in the water supply is too low.


Fluoritab Drops are a mineral. It works by strengthening the teeth and decreasing the effects of acid and bacteria on the teeth.


Do NOT use Fluoritab Drops if:


  • you are allergic to any ingredient in Fluoritab Drops

  • your drinking water has a fluoride content greater than 0.6 parts per million (ppm)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Fluoritab Drops:


Some medical conditions may interact with Fluoritab Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have joint pain, kidney problems, softening of your bones (osteomalacia, rickets), or stomach or intestinal ulcers

Some MEDICINES MAY INTERACT with Fluoritab Drops. However, no specific interactions with Fluoritab Drops are known at this time.


Ask your health care provider if Fluoritab Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Fluoritab Drops:


Use Fluoritab Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Fluoritab Drops by mouth with or without food. Do not eat or drink dairy products within 1 hour before or 2 hours after taking Fluoritab Drops.

  • Do not take an antacid that has aluminum, calcium, or magnesium in it for several hours after you take Fluoritab Drops.

  • Use the dropper that comes with Fluoritab Drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • Certain brands of Fluoritab Drops should be mixed in juice or water before you take it. Contact your doctor or pharmacist if you are unsure if you should mix Fluoritab Drops in juice or water.

  • Certain brands of Fluoritab Drops should be taken at bedtime after you brush your teeth unless your doctor tells you otherwise. Contact your doctor or pharmacist if you are unsure when to take Fluoritab Drops.

  • If you miss a dose of Fluoritab Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Fluoritab Drops.



Important safety information:


  • Do NOT use more than the dose recommended by your doctor or dentist.

  • Notify your dentist if your teeth become spotted or stained.

  • Fluoritab Drops should not be used in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.

  • Caution is advised when using Fluoritab Drops in CHILDREN younger than 6 years of age. The appropriate dose of Fluoritab Drops depends on the child's age and the amount of fluoride in the drinking water. Talk with your doctor if you have questions about the appropriate dose for your child or the amount of fluoride in your drinking water.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant while using Fluoritab Drops, contact your doctor. You will need to discuss the benefits and risks of using Fluoritab Drops while you are pregnant. It is not known if Fluoritab Drops are found in breast milk. If you are or will be breast-feeding while you are using Fluoritab Drops, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Fluoritab Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with Fluoritab Drops. Seek medical attention right away if any of these SEVERE side effects occur:



Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Fluoritab side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include bloody vomit or vomit that looks like coffee grounds; diarrhea; fast or irregular heartbeat; increased drooling; muscle weakness; nausea; seizures; slow or shallow breathing; sore tongue; stomach pain or cramping; tremor; vomiting.


Proper storage of Fluoritab Drops:

Store Fluoritab Drops at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fluoritab Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Fluoritab Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Fluoritab Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Fluoritab Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Fluoritab resources


  • Fluoritab Side Effects (in more detail)
  • Fluoritab Use in Pregnancy & Breastfeeding
  • Fluoritab Support Group
  • 0 Reviews for Fluoritab - Add your own review/rating


Compare Fluoritab with other medications


  • Prevention of Dental Caries

chloramphenicol Oral, Intravenous, Injection


klor-am-FEN-i-kol


Intravenous route(Powder for Solution)

Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, and granulocytopenia) are known to occur after the administration of chloramphenicol. There have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia. Blood dyscrasias have occurred after both short-term and prolonged therapy with this drug. It is essential that adequate blood studies be made during treatment with the drug .


Intravenous route(Powder for Solution)

Serious and fatal blood dyscrasias (aplastic anemia, hypoplastic anemia, thrombocytopenia, and granulocytopenia) are known to occur after the administration of chloramphenicol. There have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia. Blood dyscrasias have occurred after both short-term and prolonged therapy with this drug. It is essential that adequate blood studies be made during treatment with the drug .



Commonly used brand name(s)

In the U.S.


  • Chloromycetin Sodium Succinate

In Canada


  • Chloromycetin

Available Dosage Forms:


  • Capsule

  • Powder for Solution

  • Suspension

Therapeutic Class: Antibiotic


Chemical Class: Chloramphenicol (class)


Uses For chloramphenicol


Chloramphenicol is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth.


Chloramphenicol is used to treat serious infections in different parts of the body. It is sometimes given with other antibiotics. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections.


Chloramphenicol should only be used for serious infections in which other medicines do not work. chloramphenicol may cause some serious side effects, including blood problems and eye problems. Symptoms of the blood problems include pale skin, sore throat and fever, unusual bleeding or bruising, and unusual tiredness or weakness. You and your doctor should talk about the good chloramphenicol will do as well as the risks of taking it .


Chloramphenicol is available only with your doctor's prescription.


Before Using chloramphenicol


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For chloramphenicol, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to chloramphenicol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Newborn infants are especially sensitive to the side effects of chloramphenicol because they cannot remove the medicine from their body as well as older children and adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of chloramphenicol in the elderly with use in other age groups.


Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking chloramphenicol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using chloramphenicol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Citalopram

  • Voriconazole

Using chloramphenicol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Ceftazidime

  • Chlorpropamide

  • Cyclosporine

  • Dicumarol

  • Fosphenytoin

  • Phenytoin

  • Rifampin

  • Rifapentine

  • Tacrolimus

  • Tetanus Toxoid

  • Tolbutamide

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of chloramphenicol. Make sure you tell your doctor if you have any other medical problems, especially:


  • Anemia, bleeding, or other blood problems—Chloramphenicol may cause blood problems

  • Liver disease—Patients with liver disease may have an increased risk of side effects

Proper Use of chloramphenicol


Chloramphenicol is best taken with a full glass (8 ounces) of water on an empty stomach (either 1 hour before or 2 hours after meals), unless otherwise directed by your doctor.


For patients taking the oral liquid form of chloramphenicol:


  • Use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep taking chloramphenicol for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses.


Dosing


The dose of chloramphenicol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of chloramphenicol. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For infections caused by bacteria:
    • For oral dosage forms (capsules and suspension):
      • Adults and teenagers—Dose is based on body weight. The usual dose is 12.5 milligrams (mg) per kilogram (kg) (5.7 mg per pound) of body weight every six hours.

      • Children—
        • Infants up to 2 weeks of age: Dose is based on body weight. The usual dose is 6.25 mg per kg (2.8 mg per pound) of body weight every six hours.

        • Infants 2 weeks of age and older: Dose is based on body weight. The usual dose is 12.5 mg per kg (5.7 mg per pound) of body weight every six hours; or 25 mg per kg (11.4 mg per pound) of body weight every twelve hours.



    • For injection dosage form:
      • Adults and teenagers—Dose is based on body weight. The usual dose is 12.5 mg per kg (5.7 mg per pound) of body weight every six hours.

      • Children—
        • Infants up to 2 weeks of age: Dose is based on body weight. The usual dose is 6.25 mg per kg (2.8 mg per pound) of body weight every six hours.

        • Infants 2 weeks of age and older: Dose is based on body weight. The usual dose is 12.5 mg per kg (5.7 mg per pound) of body weight every six hours; or 25 mg per kg (11.4 mg per pound) of body weight every twelve hours.




Missed Dose


If you miss a dose of chloramphenicol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using chloramphenicol


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


It is very important that your doctor check you at regular visits for any blood problems that may be caused by chloramphenicol.


Chloramphenicol may cause blood problems. These problems may result in a greater chance of infection, slow healing, and bleeding of the gums. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. Dental work, whenever possible, should be done before you begin taking chloramphenicol or delayed until your blood counts have returned to normal. Check with your medical doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment.


For diabetic patients:


  • chloramphenicol may cause false test results with urine sugar tests. Check with your doctor before changing your diet or the dosage of your diabetes medicine.

chloramphenicol Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Stop taking chloramphenicol and get emergency help immediately if any of the following effects occur:


Rare - in babies only
  • Bloated stomach

  • drowsiness

  • gray skin color

  • low body temperature

  • uneven breathing

  • unresponsiveness

Check with your doctor immediately if any of the following side effects occur:


Less common
  • Pale skin

  • sore throat and fever

  • unusual bleeding or bruising

  • unusual tiredness or weakness (the above side effects may also occur up to weeks or months after you stop taking chloramphenicol)

Rare
  • Confusion, delirium, or headache

  • eye pain, blurred vision, or loss of vision

  • numbness, tingling, burning pain, or weakness in the hands or feet

  • skin rash, fever, or difficulty in breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common
  • Diarrhea

  • nausea or vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More chloramphenicol Oral, Intravenous, Injection resources


  • Chloramphenicol Oral, Intravenous, Injection Use in Pregnancy & Breastfeeding
  • Chloramphenicol Oral, Intravenous, Injection Drug Interactions
  • Chloramphenicol Oral, Intravenous, Injection Support Group
  • 0 Reviews for Chloramphenicol Oral, Intravenous, Injection - Add your own review/rating


Compare chloramphenicol Oral, Intravenous, Injection with other medications


  • Anthrax
  • Bacterial Infection
  • Brucellosis
  • Cholera
  • Glanders
  • Meningitis
  • Ornithosis
  • Plague
  • Psittacosis
  • Rabbit Fever
  • Rickettsial Infection

famciclovir


fam-SYE-kloe-vir


Commonly used brand name(s)

In the U.S.


  • Famvir

Available Dosage Forms:


  • Tablet

Therapeutic Class: Antiviral


Chemical Class: Guanosine Nucleoside Analog


Uses For famciclovir


Famciclovir is used to treat the symptoms of herpes zoster (also known as shingles), a herpes virus infection of the skin. It is used to treat and suppress herpes labialis (cold sores) and recurrent episodes of genital herpes infection. famciclovir is also used to treat recurrent herpes virus infections of the mucous membranes (lips and mouth) and genitals in HIV-infected patients. Although famciclovir will not cure genital herpes or herpes zoster, it does help relieve the pain and discomfort and helps the sores heal faster.


famciclovir is available only with your doctor's prescription.


Before Using famciclovir


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For famciclovir, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to famciclovir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


No information is available on the relationship of age to the effects of famciclovir in children under 18 years of age. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of famciclovir in the elderly. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment of dose in patients receiving famciclovir.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of famciclovir. Make sure you tell your doctor if you have any other medical problems, especially:


  • Galactose intolerance or

  • Glucose-galactose malabsorption or

  • Severe lactase deficiency—Should not use in patients with these conditions.

  • Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of famciclovir


Famciclovir is best used within 48 hours after the symptoms of shingles (for example, pain, burning, blisters) begin to appear, or within 6 hours after the symptoms of recurrent genital herpes (for example, pain, blisters) begin to appear.


Famciclovir may be taken with or without food.


To help clear up your herpes infection, keep taking famciclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses and do not use famciclovir more often or for a longer time than your doctor ordered.


Dosing


The dose of famciclovir will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of famciclovir. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For treatment of shingles:
      • Adults—500 milligrams (mg) every eight hours for seven days.

      • Children—Use and dose must be determined by your doctor.


    • For suppression of recurrent genital herpes:
      • Adults—250 milligrams (mg) two times a day for up to one year.

      • Children—Use and dose must be determined by your doctor.


    • For treatment of recurrent genital herpes:
      • Adults—1000 milligrams (mg) two times a day for one day.

      • Children—Use and dose must be determined by your doctor.


    • For treatment of recurrent herpes labialis (cold sores):
      • Adults—1500 milligrams (mg) as a single dose.

      • Children—Use and dose must be determined by your doctor.


    • For treatment of recurrent herpes infections in HIV-infected patients:
      • Adults—500 milligrams (mg) two times a day for seven days.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of famciclovir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using famciclovir


If your symptoms do not improve within a few days, or if they become worse, check with your doctor.


The areas affected by herpes should be kept as clean and dry as possible. Also, wear loose-fitting clothing to avoid irritating the sores (blisters).


famciclovir may cause some people to become dizzy, drowsy, or less alert than they are normally. If any of these side effects occur, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert while you are taking famciclovir.


famciclovir does not prevent the sexual transmission of genital herpes. You should avoid having sex when lesions are present to avoid infecting your partner.


famciclovir Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


Incidence not known
  • Black, tarry stools

  • bleeding gums

  • blistering, peeling, or loosening of the skin

  • blood in urine or stools

  • chills

  • clay-colored stools

  • cough

  • dark urine

  • dizziness

  • fever

  • joint or muscle pain

  • loss of appetite

  • pinpoint red spots on the skin

  • red, irritated eyes

  • sore throat

  • sores, ulcers, or white spots in the mouth or on the lips

  • unpleasant breath odor

  • unusual bleeding or bruising

  • vomiting of blood

  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Cramps

  • diarrhea

  • headache

  • heavy bleeding

  • nausea

  • stomach pain

Less common
  • Bloated, full feeling

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feeling

  • confusion as to time, place, or person

  • excess air or gas in the stomach or intestines

  • hives or welts

  • holding false beliefs that cannot be changed by fact

  • itching skin

  • mood or mental changes

  • passing gas

  • rash

  • redness of skin

  • seeing, hearing, or feeling things that are not there

  • unusual excitement, nervousness, or restlessness

  • unusual tiredness or weakness

  • vomiting

Incidence not known
  • Sleepiness or unusual drowsiness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: famciclovir side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More famciclovir resources


  • Famciclovir Side Effects (in more detail)
  • Famciclovir Dosage
  • Famciclovir Use in Pregnancy & Breastfeeding
  • Drug Images
  • Famciclovir Drug Interactions
  • Famciclovir Support Group
  • 14 Reviews for Famciclovir - Add your own review/rating


  • Famciclovir Prescribing Information (FDA)

  • Famciclovir Professional Patient Advice (Wolters Kluwer)

  • Famciclovir Monograph (AHFS DI)

  • Famciclovir MedFacts Consumer Leaflet (Wolters Kluwer)

  • Famvir Prescribing Information (FDA)

  • Famvir Consumer Overview



Compare famciclovir with other medications


  • Cold Sores
  • Herpes Simplex, Mucocutaneous/Immunocompetent Host
  • Herpes Simplex, Mucocutaneous/Immunocompromised Host
  • Herpes Simplex, Suppression
  • Herpes Zoster

Saturday, 26 May 2012

PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride





Dosage Form: powder, for oral solution
PEG-3350 & ELECTROLYTES FOR ORAL SOLUTION

Rx Only

DESCRIPTION:


PEG-3350 & ELECTROLYTES is a colon lavage preparation provided as water-soluble components for solution. In solution each PEG-3350 & ELECTROLYTES preparation delivers the following, in grams per liter.













Polyethylene glycol 335060.00
Sodium chloride1.46
Potassium chloride0.745
Sodium bicarbonate1.68
Sodium sulfate5.68

When dissolved in sufficient water to make 4 liters, the final solution contains

125 mEq/L sodium, 10 mEq/L potassium, 20 mEq/L bicarbonate, 80 mEq/L sulfate,

35 mEq/L chloride and 18 mEq/L polyethylene glycol 3350. The reconstituted solution is isosmotic and has a mildly salty taste. PEG-3350 & ELECTROLYTES is administered orally or via nasogastric tube.



CLINICAL PHARMACOLOGY:


PEG-3350 & ELECTROLYTES cleanses the bowel by induction of diarrhea. The osmotic activity of polyethylene glycol 3350, in combination with the electrolyte concentration, results in virtually no net absorption or excretion of ions or water. Accordingly, large volumes may be administered without significant changes in fluid and electrolyte balance.



INDICATIONS AND USAGE:


PEG-3350 & ELECTROLYTES is indicated for bowel cleansing prior to colonoscopy or barium enema X-ray examination.



CONTRAINDICATIONS:


PEG-3350 & ELECTROLYTES is contraindicated in patients known to be hypersensitive to any of the components. PEG-3350 & ELECTROLYTES is contraindicated in patients with ileus, gastrointestinal obstruction, gastric retention, bowel perforation, toxic colitis or toxic megacolon.



WARNINGS:


No additional ingredients (e.g., flavorings) should be added to the solution. PEG-3350 & ELECTROLYTES should be used with caution in patients with severe ulcerative colitis.



PRECAUTIONS:



General:


Patients with impaired gag reflex, unconscious or semiconscious patients and patients prone to regurgitation or aspiration should be observed during the administration of PEG-3350 & ELECTROLYTES, especially if it is administered via nasogastric tube.


If gastrointestinal obstruction or perforation is suspected appropriate studies should be performed to rule out these conditions before administration of PEG-3350 & ELECTROLYTES.



INFORMATION FOR PATIENTS:


PEG-3350 & ELECTROLYTES produces a watery stool which cleanses the bowel prior to examination.


For best results, no solid food should be ingested during the 3 – 4 hour period prior to the initiation of PEG-3350 & ELECTROLYTES administration. In no case should solid foods be eaten within 2 hours of drinking PEG-3350 & ELECTROLYTES.


The rate of administration is 240 mL (8 fl. oz.) every 10 minutes. Rapid drinking of each portion is preferred rather than drinking small amounts continuously.


The first bowel movement should occur approximately one hour after the start of PEG-3350 & ELECTROLYTES administration.


Administration of PEG-3350 & ELECTROLYTES should be continued until the watery stool is clear and free of solid matter. This normally requires the consumption of approximately

3–4 liters (3–4 quarts), although more or less may be required in some patients. The unused portion should be discarded.



DRUG INTERACTIONS:


Oral medication administered within one hour of the start of administration of PEG-3350 & ELECTROLYTES may be flushed from the gastrointestinal tract and not absorbed.



CARCINOGENESIS, MUTAGENESIS, IMPAIRMENT OF FERTILITY:


Studies to evaluate carcinogenic or mutagenic potential or potential to adversely affect male or female fertility have not been performed.



PREGNANCY:


Category C

Animal reproduction studies have not been conducted with PEG-3350 & ELECTROLYTES, and it is not known whether PEG-3350 & ELECTROLYTES can affect reproductive capacity or harm the fetus when administered to a pregnant patient. PEG-3350 & ELECTROLYTES should be given to a pregnant patient only if clearly needed.



PEDIATRIC USE:


Safety and effectiveness in pediatric patients have not been established.



GERIATRIC USE:


Published literature contains isolated reports of serious adverse reactions following the administration of PEG-ELS products in patients over 60 years of age. These adverse events include upper GI bleeding from Mallory-Weiss Tear, esophageal perforation, asystole, sudden dyspnea with pulmonary edema, and "butterfly-like" infiltrate on chest x-ray after vomiting and aspirating PEG.



ADVERSE REACTIONS:


Nausea, abdominal fullness and bloating are the most frequent adverse reactions, occurring in up to 50% of patients. Abdominal cramps, vomiting and anal irritation occur less frequently. These adverse reactions are transient. Isolated cases of urticaria, rhinorrhea, dermatitis, and rarely anaphylaxis, angioedema, tongue edema, and face edema have been reported which may represent allergic reactions.



DOSAGE AND ADMINISTRATION:


PEG-3350 & ELECTROLYTES can be administered orally or by nasogastric tube. Patients should fast at least 3 hours prior to administration. A one hour waiting period after the appearance of clear liquid stool should be allowed prior to examination to complete bowel evacuation. No foods except clear liquids should be permitted prior to examination after PEG-3350 & ELECTROLYTES administration.



ORAL:


The recommended adult oral dose is 240 mL (8 fl. oz.) every 10 minutes (see INFORMATION FOR PATIENTS). Lavage is complete when fecal discharge is clear. Lavage is usually complete after the ingestion of 3–4 liters.



NASOGASTRIC TUBE:


PEG-3350 & ELECTROLYTES is administered at a rate of


20-30 mL per minute (1.2-1.8 L/hour).



PREPARATION OF PEG-3350 & ELECTROLYTES SOLUTION:


4 Liter: Add tap water to FILL line. Replace cap tightly and mix or shake well until all ingredients have dissolved. (No additional ingredients, e.g. flavorings, should be added to the solution.)



HOW SUPPLIED:


PEG-3350 & ELECTROLYTES is supplied in 4 liter bottles. Each 4 liter bottle contains polyethylene glycol 3350 240 g, sodium chloride 5.84 g, potassium chloride

2.98 g, sodium bicarbonate 6.72 g, sodium sulfate (anhydrous) 22.72 g. The preparation is supplied in powdered form for oral administration as a solution.


PEG-3350 & ELECTROLYTES 4 liter NDC 62175-446-01


Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° to 30°C (59° to 86°F).


KEEP RECONSTITUTED SOLUTION REFRIGERATED. USE WITHIN 48 HOURS. DISCARD UNUSED PORTION.


Distributed by:


Kremers Urban Pharmaceuticals Inc.


Princeton, NJ 08540, USA


L2152J Rev. 3E 01/2011



INSTRUCTIONS


1.To make PEG-3350 & ELECTROLYTES solution, add tap water to the top of the FILL line marked 4 liters. Replace cap tightly and mix or shake well until ingredients have dissolved. (No additional ingredients should be added to the solution.)


2.Refrigerate the solution until ready to drink. Chilling improves the taste. Store no longer than 48 hours.


3.For best results, solid food should not be eaten during the 3 – 4 hour period before you start drinking the solution. Never eat solid food within 2 hours of drinking the solution.


4.Drink a large glassful (8 fl. oz.) of PEG-3350 & ELECTROLYTES every 10 minutes. It is best to drink the PEG-3350 & ELECTROLYTES rapidly, rather than sipping slowly. Continue drinking a glassful every 10 minutes until your watery stool is clear and free of solid matter. This normally requires drinking approximately 3 – 4 liters (3 – 4 quarts). Using the bottle marks as a guide this means either the entire bottle should be empty (4 liters consumed), or the solution should be at or below the 1 liter mark (at least 3 liters consumed).


KEEP RECONSTITUTED SOLUTION REFRIGERATED.


USE WITHIN 48 HOURS. DISCARD UNUSED PORTION.


DATE RECONSTITUTED: _____________TIME RECONSTITUTED: ____________



PRINCIPAL DISPLAY PANEL - 4 Liter Bottle Label


PEEL HERE


NDC 62175-446-01


Note to pharmacist: See base label for

mixing information. Package insert

enclosed. Remove before dispensing.


PEG-3350 & ELECTROLYTES

for Oral Solution


Rx Only


L2152J Rev. 3E 01/2011
















4 Liters
This bottle contains the following ingredients:
Polyethylene glycol 3350240.00 grams
Sodium Chloride5.84 grams
Potassium Chloride2.98 grams
Sodium bicarbonate6.72 grams
Sodium sulfate (anhydrous)22.72 grams
When dissolved in sufficient water to make 4 liters, the final solution

contains 125 mEq/L sodium, 10 mEq/L potassium, 20 mEq/L

bicarbonate, 80 mEq/L sulfate, 35 mEq/L chloride and 18 mEq/L

polyethylene glycol 3350.

Store at 20° to 25°C (68° to 77°F); excursions permitted between

15° to 30°C (59° to 86°F)


KEEP RECONSTITUTED SOLUTION REFRIGERATED.

USE WITHIN 48 HOURS. DISCARD UNUSED

PORTION.


APPROXIMATE NET WEIGHT: 278 GRAMS


L2152J










PEG-3350 AND ELECTROLYTES 
polyethylene glycol 3350, sodium chloride, potassium chloride, sodium bicarbonate, and sodium sulfate  powder, for solution










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)62175-446
Route of AdministrationORALDEA Schedule    




















Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
POLYETHYLENE GLYCOL 3350 (POLYETHYLENE GLYCOL 3350)POLYETHYLENE GLYCOL 3350240 g  in 4 L
SODIUM CHLORIDE (SODIUM CATION)SODIUM CHLORIDE5.84 g  in 4 L
POTASSIUM CHLORIDE (POTASSIUM CATION)POTASSIUM CHLORIDE2.98 g  in 4 L
SODIUM BICARBONATE (SODIUM CATION)SODIUM BICARBONATE6.72 g  in 4 L
SODIUM SULFATE (SODIUM CATION)SODIUM SULFATE22.72 g  in 4 L





Inactive Ingredients
Ingredient NameStrength
No Inactive Ingredients Found


















Product Characteristics
ColorWHITEScore    
ShapeSize
FlavorImprint Code
Contains      










Packaging
#NDCPackage DescriptionMultilevel Packaging
162175-446-014 L In 1 BOTTLENone










Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
NDA authorized genericNDA01898310/26/1984


Labeler - Kremers Urban Pharmaceuticals Inc. (006422406)
Revised: 01/2011Kremers Urban Pharmaceuticals Inc.




More PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride resources


  • PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride Use in Pregnancy & Breastfeeding
  • PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride Support Group
  • 39 Reviews for PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride - Add your own review/rating


Compare PEG-3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride with other medications


  • Bowel Preparation
  • Constipation, Chronic
  • Gastrointestinal Decontamination

Friday, 25 May 2012

Kytril


Pronunciation: gra-NIS-e-tron
Generic Name: Granisetron
Brand Name: Kytril


Kytril is used for:

Preventing nausea and vomiting caused by cancer chemotherapy and surgery. It may also be used for other conditions as determined by your doctor.


Kytril is a 5-HT3 receptor antagonist. It works by blocking a chemical called serotonin that can cause vomiting.


Do NOT use Kytril if:


  • you are allergic to any ingredient in Kytril

  • you are taking apomorphine

Contact your doctor or health care provider right away if any of these apply to you.



Before using Kytril:


Some medical conditions may interact with Kytril. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you are allergic to other 5-HT3 receptor antagonists (eg, ondansetron)

  • if you have heart problems (eg, irregular heartbeat, conduction problems), blood electrolyte problems (eg, low calcium, potassium, or magnesium), an abnormal electrocardiogram (ECG), or you are receiving chemotherapy that may cause heart problems

  • if you have stomach or bowel problems (eg, pain, swelling) or if you have recently had stomach surgery

Some MEDICINES MAY INTERACT with Kytril. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Apomorphine because the risk of side effects, such as severely low blood pressure or loss of consciousness, may occur

  • Medicines that may affect your heartbeat such as antiarrhythmics (eg, flecainide, sotalol), azole antifungals (eg, ketoconazole), or quinolones (eg, ciprofloxacin) because heart rhythm problems may occur. Ask your doctor if you are unsure if any medicines that you take may affect your heartbeat

This may not be a complete list of all interactions that may occur. Ask your health care provider if Kytril may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Kytril:


Use Kytril as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Kytril is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Kytril at home, a health care provider will teach you how to use it. Be sure you understand how to use Kytril. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Do not use Kytril if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Kytril, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Kytril.



Important safety information:


  • Kytril may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Kytril with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Some forms of this product contain benzyl alcohol, which may cause a severe and sometimes fatal reaction known as "gasping syndrome" in premature, newborn, or low birth-weight infants. Ask your doctor or pharmacist if Kytril contains benzyl alcohol. Use Kytril with extreme caution in premature, newborn, or low birth-weight infants.

  • Kytril should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Kytril while you are pregnant. It is not known if Kytril is found in breast milk. If you are or will be breast-feeding while you are using Kytril, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Kytril:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Agitation; anxiety; constipation; diarrhea; dizziness; drowsiness; headache; indigestion; nausea; pain, swelling, or redness at the injection site; stomach pain; taste changes; trouble sleeping; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fainting; fast or irregular heartbeat; fever, chills, or sore throat; unusual muscle movement.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Kytril side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include headache.


Proper storage of Kytril:

Kytril is usually handled and stored by a health care provider. If you are using Kytril at home, store Kytril as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Kytril out of the reach of children and away from pets.


General information:


  • If you have any questions about Kytril, please talk with your doctor, pharmacist, or other health care provider.

  • Kytril is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Kytril. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Kytril resources


  • Kytril Side Effects (in more detail)
  • Kytril Use in Pregnancy & Breastfeeding
  • Drug Images
  • Kytril Drug Interactions
  • Kytril Support Group
  • 2 Reviews for Kytril - Add your own review/rating


  • Kytril Prescribing Information (FDA)

  • Kytril Consumer Overview

  • Kytril Monograph (AHFS DI)

  • Kytril Advanced Consumer (Micromedex) - Includes Dosage Information

  • Granisetron Prescribing Information (FDA)

  • Granisol Prescribing Information (FDA)

  • Sancuso Prescribing Information (FDA)

  • Sancuso Consumer Overview

  • Sancuso Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Kytril with other medications


  • Nausea/Vomiting, Chemotherapy Induced
  • Nausea/Vomiting, Postoperative
  • Nausea/Vomiting, Radiation Induced

Wednesday, 23 May 2012

amlodipine and atorvastatin


Generic Name: amlodipine and atorvastatin (am LOE di peen and a TOR va sta tin)

Brand Names: Caduet


What is amlodipine and atorvastatin?

Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Amlodipine and atorvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).


Amlodipine is in a group of drugs called calcium channel blockers. Amlodipine relaxes the blood vessels, improving blood flow and making it easier for the heart to pump.


The combination of amlodipine and atorvastatin is used to treat high blood pressure (hypertension) or chest pain (angina), and to lower the risk of stroke, heart attack, and other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.


Amlodipine and atorvastatin is used in adults and children who are at least 10 years old.


Amlodipine and atorvastatin may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about amlodipine and atorvastatin?


You should not use this medication if you are allergic to amlodipine (Norvasc) or atorvastatin (Lipitor), if you are pregnant or breast-feeding, or if you have liver disease. Stop taking this medication and tell your doctor right away if you become pregnant.

Before taking amlodipine and atorvastatin, tell your doctor if you have ever had liver or kidney disease, heart disease, diabetes, or a thyroid disorder, or if you drink more than 2 alcoholic beverages daily.


In rare cases, amlodipine and atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Avoid eating foods that are high in fat or cholesterol. Amlodipine and atorvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.


Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

There are many other drugs that can increase your risk of serious medical problems if you take them together with amlodipine and atorvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.


Amlodipine and atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.


What should I discuss with my healthcare provider before taking amlodipine and atorvastatin?


You should not use this medication if you are allergic to amlodipine (Norvasc) or atorvastatin (Lipitor), if you are pregnant or breast-feeding, or if you have liver disease.

If you have any of these other conditions, you may need a dose adjustment or special tests:


  • history of liver disease;

  • history of kidney disease;


  • heart disease;




  • diabetes;




  • a thyroid disorder; or




  • if you drink more than 2 alcoholic beverages daily.




In rare cases, amlodipine and atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

Tell your doctor about all other medications you use. Certain other drugs can increase your risk of serious muscle problems, and it is very important that your doctor knows if you are using any of them:



  • cyclosporine (Gengraf, Neoral, Sandimmune);




  • gemfibrozil (Lopid), fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);




  • antibiotics such as clarithromycin (Biaxin) or erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin);




  • antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), or ketoconazole (Extina, Ketozole, Nizoral, Xolegal);




  • HIV medications such as ritonavir (Norvir), lopinavir/ritonavir (Kaletra), saquinavir (Invirase), and others; or




  • medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others).




FDA pregnancy category X. This medication can harm an unborn baby or cause birth defects. Do not take amlodipine and atorvastatin if you are pregnant. Stop taking this medication and tell your doctor right away if you become pregnant. Use effective birth control to avoid pregnancy while you are taking amlodipine and atorvastatin. Amlodipine and atorvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking amlodipine and atorvastatin.

How should I take amlodipine and atorvastatin?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Amlodipine and atorvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day. Your doctor may occasionally change your dose to make sure you get the best results.


Do not break an amlodipine and atorvastatin tablet. Tell your doctor if you have trouble swallowing the pill.


You may need to stop using amlodipine and atorvastatin for a short time if you have:

  • uncontrolled seizures;




  • an electrolyte imbalance (such as high or low potassium levels in your blood);




  • severely low blood pressure;




  • a severe infection or illness; or




  • surgery or a medical emergency.



To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.


Amlodipine and atorvastatin is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely.


You may need to take amlodipine and atorvastatin on a long-term basis for the treatment of high cholesterol. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms. Store at room temperature away from moisture and heat.

See also: Amlodipine and atorvastatin dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 12 hours away. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heart rate, feeling light-headed, fainting, and severe warmth, redness or tingly feeling.


What should I avoid while taking amlodipine and atorvastatin?


Avoid eating foods that are high in fat or cholesterol. This medication will not be as effective in treating your condition if you do not follow the diet plan recommended by your doctor.


Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage. Alcohol can also further lower blood pressure and can increase some of the side effects of amlodipine and atorvastatin.

Grapefruit and grapefruit juice may interact with amlodipine and atorvastatin and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.


Amlodipine and atorvastatin side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking this medicine and call your doctor at once if you have any of these serious side effects:

  • unexplained muscle pain, tenderness, or weakness;




  • fever, unusual tiredness, and dark colored urine;




  • swelling, weight gain, urinating less than usual or not at all;




  • severe drowsiness, feeling like you might pass out;




  • fast or pounding heartbeats;




  • worsening chest pain;




  • chest pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or




  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • headache;




  • mild muscle pain;




  • diarrhea;




  • mild nausea;




  • stomach pain or indigestion;




  • dizziness;




  • joint pain; or




  • flushing (warmth or redness in your face).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Amlodipine and atorvastatin Dosing Information


Usual Adult Dose for Hypertension:

Initial dose: Individualize based on the effectiveness and tolerance for each individual component. Generally the initial starting dose for each component is amlodipine 5 mg orally once a day and atorvastatin 10, 20, or 40 mg orally once a day.

Maintenance dose: amlodipine 5 mg to 10 mg orally once a day, and atorvastatin 10 mg to 80 mg once a day.

Usual Adult Dose for Angina Pectoris:

Initial dose: Individualize based on the effectiveness and tolerance for each individual component. Generally the initial starting dose for each component is amlodipine 5 mg orally once a day and atorvastatin 10, 20, or 40 mg orally once a day.

Maintenance dose: amlodipine 5 mg to 10 mg orally once a day, and atorvastatin 10 mg to 80 mg once a day.


What other drugs will affect amlodipine and atorvastatin?


Tell your doctor about all other medications you use, especially:



  • birth control pills;




  • a blood thinner such as warfarin (Coumadin);




  • cimetidine (Tagamet);




  • digoxin (Lanoxin);




  • diltiazem (Cartia, Cardizem);




  • efavirenz (Sustiva, Atripla);




  • nitroglycerin (Nitro-Dur, Nitrolingual, Nitrostat, Transderm-Nitro, and others),




  • rifampin (Rifater, Rifadin, Rifamate);




  • spironolactone (Aldactone, Aldactazide); or




  • any other "statin" medication such as atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), or simvastatin (Zocor, Simcor, Vytorin).



This list is not complete and other drugs may interact with amlodipine and atorvastatin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More amlodipine and atorvastatin resources


  • Amlodipine and atorvastatin Side Effects (in more detail)
  • Amlodipine and atorvastatin Dosage
  • Amlodipine and atorvastatin Use in Pregnancy & Breastfeeding
  • Drug Images
  • Amlodipine and atorvastatin Drug Interactions
  • Amlodipine and atorvastatin Support Group
  • 3 Reviews for Amlodipine and atorvastatin - Add your own review/rating


Compare amlodipine and atorvastatin with other medications


  • Angina
  • High Blood Pressure


Where can I get more information?


  • Your pharmacist can provide more information about amlodipine and atorvastatin.

See also: amlodipine and atorvastatin side effects (in more detail)