Brunacol may be available in the countries listed below.
Ketorolac tromethamine (a derivative of Ketorolac) is reported as an ingredient of Brunacol in the following countries:
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Citalopram Depronal may be available in the countries listed below.
Citalopram hydrobromide (a derivative of Citalopram) is reported as an ingredient of Citalopram Depronal in the following countries:
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Generic Name: denosumab (Xgeva) (den OH sue mab)
Brand Names: Xgeva
Denosumab is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.
The Xgeva brand of denosumab is used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Xgeva is not for use in people with multiple myeloma (bone marrow cancer).
This medication guide provides information about the Xgeva brand of denosumab. Prolia is another brand of denosumab used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.
Denosumab may also be used for purposes not listed in this medication guide.
This medication guide provides information about the Xgeva brand of denosumab. Prolia is another brand of denosumab used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.
Before you receive this medication, tell your doctor if you have kidney disease or if you are on dialysis.
Some people using denosumab have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
To make sure you can safely use Xgeva, tell your doctor if you have kidney disease or if you are on dialysis.
Some people using denosumab have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.
Denosumab is injected under the skin of your stomach, upper thigh, or upper arm. A healthcare provider will give you this injection.
Xgeva is usually given once every 4 weeks. Follow your doctor's instructions.
Your doctor may have you take extra calcium and vitamin D while you are being treated with denosumab. Take only the amount of calcium and vitamin D that your doctor has prescribed.
Pay special attention to your dental hygiene. Brush and floss your teeth regularly while receiving this medication. You may need to have a dental exam before you begin treatment with Xgeva. Follow your doctor's instructions.
You may take the medicine out of the refrigerator and allow it to reach room temperature before giving the injection. Do not heat the medicine before using.
Each single use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.
Call your doctor for instructions if you miss an appointment for your Xgeva injection.
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
numbness or tingly feeling around your mouth or in your fingers or toes, fast or slow heart rate, muscle cramps or contraction, overactive reflexes; or
trouble breathing.
Less serious side effects may include:
feeling weak or tired;
diarrhea, nausea; or
headache.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Osteoporosis:
For the treatment of postmenopausal women with osteoporosis at high risk for fracture, defined as a history of osteoporotic fracture, or multiple risk factors for fracture; or patients who have failed or are intolerant to other available osteoporosis therapy, treatment to increase bone mass in women at high risk for fracture
receiving adjuvant aromatase inhibitor therapy for breast cancer, and treatment to increase bone mass in men at high risk for fracture receiving androgen deprivation therapy for nonmetastatic prostate cancer:
60 mg administered as a single subcutaneous injection in the upper arm, the upper thigh, or the abdomen once every 6 months. All patients should receive calcium 1000 mg daily and at least 400 IU vitamin D daily
Usual Adult Dose for Hypercalcemia of Malignancy:
For the prevention of skeletal related events in patients with bone metastases from solid tumors:
120 mg as a subcutaneous injection in the upper arm, upper thigh, or abdomen every 4 weeks.
Administer calcium and vitamin D as necessary to treat or prevent hypocalcemia.
There may be other drugs that can interact with Xgeva. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
See also: denosumab side effects (in more detail)
Doabetic may be available in the countries listed below.
Glibenclamide is reported as an ingredient of Doabetic in the following countries:
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Leustat may be available in the countries listed below.
UK matches:
Cladribine is reported as an ingredient of Leustat in the following countries:
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Glossary
| SPC | Summary of Product Characteristics (UK) |
Metronidazole Teva may be available in the countries listed below.
Metronidazole is reported as an ingredient of Metronidazole Teva in the following countries:
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Diseptyl may be available in the countries listed below.
Sulfamethoxazole is reported as an ingredient of Diseptyl in the following countries:
Trimethoprim is reported as an ingredient of Diseptyl in the following countries:
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Metronidazol Genericon may be available in the countries listed below.
Metronidazole is reported as an ingredient of Metronidazol Genericon in the following countries:
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Ibuphil may be available in the countries listed below.
Ibuprofen is reported as an ingredient of Ibuphil in the following countries:
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Tamoa may be available in the countries listed below.
Pyrantel embonate (a derivative of Pyrantel) is reported as an ingredient of Tamoa in the following countries:
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Co-Trimoxazol PCH may be available in the countries listed below.
Sulfamethoxazole is reported as an ingredient of Co-Trimoxazol PCH in the following countries:
Trimethoprim is reported as an ingredient of Co-Trimoxazol PCH in the following countries:
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Noax may be available in the countries listed below.
Tramadol is reported as an ingredient of Noax in the following countries:
Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Noax in the following countries:
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Cortamethasone may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Dexamethasone is reported as an ingredient of Cortamethasone in the following countries:
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StrontPol may be available in the countries listed below.
Strontium Chloride Sr 89 is reported as an ingredient of StrontPol in the following countries:
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Ciprofloxacina Ciclum may be available in the countries listed below.
Ciprofloxacin is reported as an ingredient of Ciprofloxacina Ciclum in the following countries:
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Cloxi-Z may be available in the countries listed below.
Cloxacillin sodium salt (a derivative of Cloxacillin) is reported as an ingredient of Cloxi-Z in the following countries:
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Cervagem may be available in the countries listed below.
Gemeprost is reported as an ingredient of Cervagem in the following countries:
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Meclophen may be available in the countries listed below.
Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Meclophen in the following countries:
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